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CS-W001157 4
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2-Amino-1H-benzo[d]imidazole-4-carboxylic acid

  • CAS No. 716362-36-6

  • Cat. No. CS-0523855
  • Molecule weight177.16
  • Purity≥97%
  • MDL No.MFCD06797233

*For research and further manufacturing use only, not for direct human use.

2-Amino-1H-benzo[d]imidazole-4-carboxylic acid|CS-0523855

Structure of 716362-36-6

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General Information

  • CAS No. 716362-36-6
  • Cat. No. CS-0523855
  • Purity ≥97%
  • MDL No. MFCD06797233
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃O₂
  • Molecular Weight 177.16
  • Synonym(s) 1H-Benzimidazole-4-carboxylic acid, 2-amino- (9CI)
  • SMILES O=C(C1=C2N=C(N)NC2=CC=C1)O

Description

2-Amino-1H-benzo[d]imidazole-4-carboxylic acid features a fused heterocyclic core with complementary amine and carboxylic acid functionalities, enabling direct incorporation into bioactive scaffolds. This robust, bench-stable compound integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents.

Application

2-Amino-1H-benzo[d]imidazole-4-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its dual amino and carboxylic acid functionalities enable facile derivatization via amide coupling, amidation, or metal-catalyzed cross-coupling reactions. The scaffold exhibits good bench stability and facilitates purification through standard crystallization or chromatographic methods, making it well-suited for iterative synthesis workflows in API development and functionalized aromatic system construction.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   92
  • LogP   0.8433
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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