Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Amino-1H-benzo[d]imidazole-5-carboxylic acid

  • CAS No. 76391-97-4

  • Cat. No. CS-0060644
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Amino-1H-benzo[d]imidazole-5-carboxylic acid|CS-0060644

Structure of 76391-97-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 76391-97-4
  • Cat. No. CS-0060644
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃O₂
  • Molecular Weight 177.16
  • Synonym(s) 2-AMINO-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID
  • SMILES O=C(O)C1=CC(NC(N)=N2)=C2C=C1

Description

This heterocyclic carboxylic acid integrates a fused imidazole core with amino and carboxylate functionalities, enabling direct conjugation in bioconjugation and medicinal chemistry applications. The electron-rich aromatic system supports metal coordination and facilitates synthetic elaboration under standard conditions.

Application

2-Amino-1H-benzo[d]imidazole-5-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its dual amino and carboxylic acid functionalities enable straightforward derivatization via amide coupling, amidation, or metal-catalyzed cross-coupling reactions. The scaffold exhibits good bench stability and facilitates purification through standard recrystallization or chromatographic methods, making it well-suited for high-throughput synthesis of bioactive molecules and API intermediates.

Synthesis

  • Route1
    • null|null
      506-68-3
    • In-stock
      Methyl 3,4-diaminobenzoate|CS-W007431
      36692-49-6
    • ~96%
    • In-stock
      2-Amino-1H-benzo[d]imidazole-5-carboxylic acid|CS-0060644
      76391-97-4

    References

    • PFIZER INC. Patent: US2012/270893 A1, 2012 ; Location in patent: Page/Page column 27 ;
  • Route2

    References

    • Dellweg et al. Biochemische Zeitschrift, 1956 , vol. 327, p. 422,447
  • Route3
    • null|null
      148720-14-3
    • ~%
    • In-stock
      2-Amino-1H-benzo[d]imidazole-5-carboxylic acid|CS-0060644
      76391-97-4

    References

    • Nakayama; Taira; Ikeda; Ashizawa; Oda; Arakawa; Fujii Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 1 p. 117 - 125

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   92
  • LogP   0.8433
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 76391-97-4 sigma76391-97-4 manufacturer76391-97-4 price76391-97-4 structure76391-97-4 SDSbuy 76391-97-476391-97-4 supplier76391-97-4 uses76391-97-4 molecular weightprice of 76391-97-476391-97-4 chemical name formula of 76391-97-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label