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CS-W001157 4
Total: USD 88.00

N-benzyl-2-chloropyrimidin-4-amine

  • CAS No. 71406-74-1

  • Cat. No. CS-0331270
  • Molecule weight219.67
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-benzyl-2-chloropyrimidin-4-amine|CS-0331270

Structure of 71406-74-1

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General Information

  • CAS No. 71406-74-1
  • Cat. No. CS-0331270
  • Purity ≥95%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀ClN₃
  • Molecular Weight 219.67
  • Synonym(s) N-BENZYL-N-(2-CHLOROPYRIMIDIN-4-YL)AMINE
  • SMILES ClC1=NC=CC(NCC2=CC=CC=C2)=N1

Synthesis

  • Route1
    • null|null
      3934-20-1
    • null|null
      100-46-9
    • ~70%
    • N-benzyl-2-chloropyrimidin-4-amine|CS-0331270
      71406-74-1

    References

    • Mohamed, Tarek; Zhao, Xiaobei; Habib, Lila K.; Yang, Jerry; Rao, Praveen P.N. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 7 p. 2269 - 2281
  • Route2
    • 2,4-Dichloro-6,7-dimethoxyquinazoline Doxazosin Impurity|CS-0229599
      27631-29-4
    • null|null
      100-46-9
    • ~26%
    • N-benzyl-2-chloropyrimidin-4-amine|CS-0331270
      71406-74-1

    References

    • Chen, Kuen-Feng; Pao, Kuan-Chuan; Su, Jung-Chen; Chou, Yi-Chieh; Liu, Chun-Yu; Chen, Hui-Ju; Huang, Jui-Wen; Kim, Inki; Shiau, Chung-Wai Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 20 p. 6144 - 6153
  • Route3
    • null|null
      3934-20-1
    • null|null
      100-46-9
    • ~%
    • N-Benzyl-4-chloropyrimidin-2-amine|CS-0670621
      71406-63-8
    • N-benzyl-2-chloropyrimidin-4-amine|CS-0331270
      71406-74-1

    References

    • Coombs, Thomas C.; Tanega, Cordelle; Shen, Min; Wang, Jenna L.; Auld, Douglas S.; Gerritz, Samuel W.; Schoenen, Frank J.; Thomas, Craig J.; Aube, Jeffrey Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 12 p. 3654 - 3661

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.81
  • LogP   2.7421
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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