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2-Amino-6-phenylpyrimidin-4(3H)-one

  • CAS No. 56741-94-7

  • Cat. No. CS-0037432
  • Purity≥97%
  • MDL No.MFCD00466412

*For research and further manufacturing use only, not for direct human use.

2-Amino-6-phenylpyrimidin-4(3H)-one|CS-0037432

Structure of 56741-94-7

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General Information

  • CAS No. 56741-94-7
  • Cat. No. CS-0037432
  • Purity ≥97%
  • MDL No. MFCD00466412
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉N₃O
  • Molecular Weight 187.20
  • Synonym(s) 2-Amino-6-phenyl-pyrimidin-4-ol
  • SMILES C1=CC=C(C=C1)C2=CC(=NC(=N)N2)O

Description

2-Amino-6-phenylpyrimidin-4(3H)-one features a fused pyrimidinone core with a phenyl group at the 6-position and an amino substituent at the 2-position. This electron-rich scaffold integrates readily into heterocyclic architectures, offering enhanced solubility and stability under standard conditions. The compound serves as a key intermediate in medicinal chemistry for constructing bioactive molecules.

Application

2-Amino-6-phenylpyrimidin-4(3H)-one serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard functionalization at the amino and carbonyl positions. Its bench-stable nature and compatibility with common coupling reactions facilitate straightforward derivatization for drug discovery applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.76
  • LogP   1.26177
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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