2-Chloro-4-phenylpyrimidine

Name: 2-Chloro-4-phenylpyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 13036-50-5
Cat. No. CS-W005953
Purity≥98%
MDL No.MFCD00234600

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 13036-50-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 13036-50-5
Cat. No. CS-W005953
Purity ≥98%
MDL No. MFCD00234600
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₇ClN₂
Molecular Weight 190.63
Synonym(s) 2-chloro-4-phenyl-pyrimidin
SMILES ClC1=NC=CC(C2=CC=CC=C2)=N1

Description

2-Chloro-4-phenylpyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, featuring a chlorine substituent at the 2-position and a phenyl group at the 4-position. This arrangement imparts enhanced metabolic stability and facilitates efficient coupling in transition-metal-catalyzed reactions. The compound integrates readily into kinase inhibitor frameworks and other bioactive molecules.

Application

2-Chloro-4-phenylpyrimidine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions to construct biaryl and heteroaryl architectures. Its chlorine atom facilitates efficient functionalization under standard Suzuki-Miyaura and Buchwald-Hartwig conditions, while the phenyl-substituted pyrimidine core exhibits bench stability and compatibility with diverse reaction environments.

Synthesis

Route1
- 3934-20-1
- In-stock
  
  98-80-6
- ~86%
- In-stock
  
  13036-50-5
References
- Ceide, Susana Conde; Montalban, Antonio Garrido Tetrahedron Letters, 2006 , vol. 47, # 26 p. 4415 - 4418
Route2
- 3934-20-1
- 38111-44-3
- ~63%
- In-stock
  
  13036-50-5
References
- Bristol-Myers Squibb Company Patent: US2008/107625 A1, 2008 ; Location in patent: Page/Page column 64 ;
Route3
- In-stock
  
  1722-12-9
- 591-51-5
- ~%
- In-stock
  
  13036-50-5
References
- US2006/69110 A1, ; Page/Page column 69 ; US 20060069110 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 25.78
LogP 2.797
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Chloro-4-phenylpyrimidine sigma2-Chloro-4-phenylpyrimidine manufacturer2-Chloro-4-phenylpyrimidine price2-Chloro-4-phenylpyrimidine structure2-Chloro-4-phenylpyrimidine SDSbuy 2-Chloro-4-phenylpyrimidine2-Chloro-4-phenylpyrimidine supplier2-Chloro-4-phenylpyrimidine uses2-Chloro-4-phenylpyrimidine molecular weightprice of 2-Chloro-4-phenylpyrimidine2-Chloro-4-phenylpyrimidine chemical name formula of 2-Chloro-4-phenylpyrimidine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-4-phenylpyrimidine

CAS No. 13036-50-5

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words