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Structure of 701264-00-8
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4-(Aminomethyl)-3-fluorobenzonitrile features a fluorinated aromatic ring paired with a nitrile group and a primary amine at the benzylic position, enabling direct conjugation in bioconjugation workflows. The electron-deficient benzene core enhances reactivity in nucleophilic substitution, while the pendant amine facilitates derivatization under mild conditions. This scaffold integrates efficiently into probe design for targeted labeling and is stable under standard bench protocols.
4-(Aminomethyl)-3-fluorobenzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated aromatic scaffolds. The nitrile group facilitates downstream transformations such as amide formation or reduction to primary amines, while the ortho-fluoro substituent supports directed metallation and electrophilic substitution. Its bench-stable nature and compatibility with common coupling reactions make it well-suited for modular synthesis of bioactive compounds and API intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: