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Structure of 1261499-40-4
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5-(Aminomethyl)-2-chlorobenzonitrile features a strategically positioned nitrile group and chloro substituent on a benzene ring, enabling selective functionalization in medicinal chemistry. The aminomethyl handle facilitates conjugation or derivatization under mild conditions, offering a robust scaffold for targeted molecular design.
5-(Aminomethyl)-2-chlorobenzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds via cyclization reactions. The ortho-chloro and nitrile groups provide orthogonal reactivity for palladium-catalyzed coupling and nucleophilic addition, respectively. Its bench-stable nature and compatibility with common protecting group strategies facilitate straightforward purification and downstream functionalization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: