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CS-W001157 4
Total: USD 88.00

N-Aminomorpholine

  • CAS No. 4319-49-7

  • Cat. No. CS-W001074
  • Purity≥95%
  • MDL No.MFCD00006174

*For research and further manufacturing use only, not for direct human use.

N-Aminomorpholine|CS-W001074

Structure of 4319-49-7

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General Information

  • CAS No. 4319-49-7
  • Cat. No. CS-W001074
  • Purity ≥95%
  • MDL No. MFCD00006174
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀N₂O
  • Molecular Weight 102.14
  • Synonym(s) morpholin-4-amine
  • SMILES NN1CCOCC1

Description

N-Aminomorpholine delivers a nucleophilic amine functionality within a rigid, oxygen-rich heterocyclic framework. This bench-stable derivative integrates readily into coupling reactions, offering enhanced solubility and reactivity in synthetic transformations.

Application

N-Aminomorpholine serves as a versatile nitrogen heterocycle scaffold in synthetic organic chemistry, enabling efficient construction of bioactive molecules. Its amine-functionalized morpholine core exhibits excellent solubility and functional group tolerance, facilitating downstream derivatization via amidation, alkylation, or coupling reactions. The compound demonstrates bench stability and ease of purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      110-91-8
    • ~%
    • In-stock
      N-Aminomorpholine|CS-W001074
      4319-49-7

    References

    • USV Pharmaceutical Corp. Patent: US4564677 A1, 1986 ;
  • Route2

    References

    • Lunn, George; Sansone, Eric B.; Keefer, Larry K. Journal of Organic Chemistry, 1984 , vol. 49, # 19 p. 3470 - 3473
  • Route3
    • In-stock
      N-Nitrosomorpholine|CS-0128913
      59-89-2
    • ~31%
    • In-stock
      N-Aminomorpholine|CS-W001074
      4319-49-7
    • null|null
      57902-11-1

    References

    • Valenta, Vladimir; Holubek, Jiri; Svatek, Emil; Protiva, Miroslav Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 12 p. 3013 - 3023

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.49
  • LogP   -0.8077
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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