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CS-W001157 4
Total: USD 88.00

(R)-2,3-Dihydro-1H-inden-1-ol

  • CAS No. 697-64-3

  • Cat. No. CS-W013378
  • Purity≥98%
  • MDL No.MFCD00064164

*For research and further manufacturing use only, not for direct human use.

(R)-2,3-Dihydro-1H-inden-1-ol|CS-W013378

Structure of 697-64-3

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General Information

  • CAS No. 697-64-3
  • Cat. No. CS-W013378
  • Purity ≥98%
  • MDL No. MFCD00064164
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O
  • Molecular Weight 134.18
  • Synonym(s) (R)-(-)-1-Indanol
  • SMILES O[C@@H]1CCC2=C1C=CC=C2

Description

(R)-2,3-Dihydro-1H-inden-1-ol is a chiral building block featuring a rigid, fused bicyclic scaffold with a stereogenic center at the hydroxyl-bearing carbon. This bench-stable alcohol integrates readily into asymmetric synthesis workflows, where its defined stereochemistry enables precise control in catalytic transformations and natural product elaboration.

Application

(R)-2,3-Dihydro-1H-inden-1-ol serves as a chiral building block for asymmetric synthesis, offering a rigid, enantiomerically pure scaffold with a pendant hydroxyl group. Its bench-stable nature and compatibility with standard functional group manipulations enable efficient access to indane-based intermediates. The alcohol functionality facilitates derivatization via esterification, ether formation, or oxidation, supporting its use in medicinal chemistry and catalytic process development.

Synthesis

  • Route1
    • 1-Indanone Rasagiline  Impurity|CS-0229098
      83-33-0
    • ~99%
    • In-stock
      (R)-2,3-Dihydro-1H-inden-1-ol|CS-W013378
      697-64-3

    References

    • Teitelbaum, Aaron M.; Meissner, Anja; Harding, Ryan A.; Wong, Christopher A.; Aldrich, Courtney C.; Remmel, Rory P. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 17 p. 5605 - 5617
  • Route2
    • 2,3-Dihydro-1H-inden-1-ol|CS-0017842
      6351-10-6
    • ~0%
    • In-stock
      (R)-2,3-Dihydro-1H-inden-1-ol|CS-W013378
      697-64-3
    • In-stock
      (S)-2,3-Dihydro-1H-inden-1-ol|CS-W013372
      25501-32-0
    • 1-Indanone Rasagiline  Impurity|CS-0229098
      83-33-0

    References

    • Ferreira; Stoltz Journal of the American Chemical Society, 2001 , vol. 123, # 31 p. 7725 - 7726
  • Route3

    References

    • Hosoda, Naoya; Kamito, Hideaki; Takano, Miki; Takebe, Yoshitaka; Yamaguchi, Yoshitaka; Asami, Masatoshi Tetrahedron, 2013 , vol. 69, # 6 p. 1739 - 1746

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.6662
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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