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CS-W001157 4
Total: USD 88.00

2,3-Dihydro-1H-inden-1-ol

  • CAS No. 6351-10-6

  • Cat. No. CS-0017842
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydro-1H-inden-1-ol|CS-0017842

Structure of 6351-10-6

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General Information

  • CAS No. 6351-10-6
  • Cat. No. CS-0017842
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O
  • Molecular Weight 134.18
  • Synonym(s) 1-Indanol
  • SMILES OC1CCC2=C1C=CC=C2

Description

This bench-stable indenol features a reactive hydroxyl group flanked by a rigid bicyclic framework, enabling straightforward functionalization in synthetic transformations. Its solubility in common organic solvents supports use in catalytic reactions and as a building block for complex molecular architectures.

Application

2,3-Dihydro-1H-inden-1-ol serves as a versatile building block in synthetic organic chemistry, offering a rigid, chiral scaffold with a primary hydroxyl group. Its functionality enables straightforward derivatization via esterification, etherification, and oxidation to the corresponding aldehyde or carboxylic acid. The compound exhibits good bench stability and is compatible with standard protecting group strategies, facilitating its use in complex molecule synthesis, including heterocyclic systems and natural product analogs.

Synthesis

  • Route1
    • null|null
      880486-81-7
    • ~94%
    • 2,3-Dihydro-1H-inden-1-ol|CS-0017842
      6351-10-6

    References

    • Shirini, Farhad; Khaligh, Nader Ghaffari; Akbari-Dadamahaleh, Somayeh Journal of Molecular Catalysis A: Chemical, 2012 , vol. 365, p. 15 - 23
  • Route2
    • 1-Indanone Rasagiline  Impurity|CS-0229098
      83-33-0
    • ~99%
    • 2,3-Dihydro-1H-inden-1-ol|CS-0017842
      6351-10-6

    References

    • Clerici, Angelo; Pastori, Nadia; Porta, Ombretta European Journal of Organic Chemistry, 2001 , # 12 p. 2235 - 2243
  • Route3

    References

    • Advanced Synthesis and Catalysis, , vol. 351, # 16 p. 2638 - 2642

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.6662
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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