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CS-W001157 4
Total: USD 88.00

(S)-2,3-Dihydro-1H-inden-1-ol

  • CAS No. 25501-32-0

  • Cat. No. CS-W013372
  • Purity≥97%
  • MDL No.MFCD00064165

*For research and further manufacturing use only, not for direct human use.

(S)-2,3-Dihydro-1H-inden-1-ol|CS-W013372

Structure of 25501-32-0

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General Information

  • CAS No. 25501-32-0
  • Cat. No. CS-W013372
  • Purity ≥97%
  • MDL No. MFCD00064165
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O
  • Molecular Weight 134.18
  • Synonym(s) (S)-(+)-1-Indanol
  • SMILES O[C@H]1CCC2=C1C=CC=C2

Description

(S)-2,3-Dihydro-1H-inden-1-ol is a chiral, bench-stable building block featuring a hydroxyl group at the benzylic position of a saturated indene core. This configuration enables stereoselective transformations in asymmetric synthesis, particularly in the construction of complex polycyclic architectures. The molecule's rigid, planar framework supports predictable reactivity in transition-metal-catalyzed coupling and oxidation processes.

Application

(S)-2,3-Dihydro-1H-inden-1-ol serves as a chiral building block for asymmetric synthesis, offering a rigid, enantiomerically pure scaffold with a benzylic hydroxyl group. Its stability and compatibility with standard functional group transformations enable reliable use in medicinal chemistry and natural product synthesis. The molecule facilitates stereoselective derivatization and acts as a key intermediate in the construction of complex heterocyclic frameworks and bioactive compounds.

Synthesis

  • Route1
    • null|null
      123-20-6
    • 2,3-Dihydro-1H-inden-1-ol|CS-0017842
      6351-10-6
    • ~%
    • In-stock
      (R)-2,3-Dihydro-1H-inden-1-ol|CS-W013378
      697-64-3
    • In-stock
      (S)-2,3-Dihydro-1H-inden-1-ol|CS-W013372
      25501-32-0
    • null|null
      158529-97-6

    References

    • Tetrahedron Letters, , vol. 39, # 24 p. 4333 - 4336
  • Route2
    • 2,3-Dihydro-1H-inden-1-ol|CS-0017842
      6351-10-6
    • null|null
      100465-50-7
    • ~%
    • In-stock
      (S)-2,3-Dihydro-1H-inden-1-ol|CS-W013372
      25501-32-0
    • null|null
      158529-97-6
    • In-stock
      1,1'-Bi-2-naphthol|CS-W018498
      602-09-5

    References

    • Journal of the Chinese Chemical Society (Taipei, Taiwan), , vol. 41, # 4 p. 459 - 466
  • Route3
    • 2,3-Dihydro-1H-inden-1-ol|CS-0017842
      6351-10-6
    • ~25%
    • In-stock
      (S)-2,3-Dihydro-1H-inden-1-ol|CS-W013372
      25501-32-0

    References

    • Dearden, Michael J.; Firkin, Catherine R.; Hermet, Jean-Paul R.; O'Brien, Peter Journal of the American Chemical Society, 2002 , vol. 124, # 40 p. 11870 - 11871

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.6662
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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