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CS-W001157 4
Total: USD 88.00

4-(1-Hydroxyethyl)phenol

  • CAS No. 2380-91-8

  • Cat. No. CS-W006209
  • Purity≥98%
  • MDL No.MFCD00016858

*For research and further manufacturing use only, not for direct human use.

4-(1-Hydroxyethyl)phenol|CS-W006209

Structure of 2380-91-8

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General Information

  • CAS No. 2380-91-8
  • Cat. No. CS-W006209
  • Purity ≥98%
  • MDL No. MFCD00016858
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀O₂
  • Molecular Weight 138.16
  • Synonym(s) 4-Hydroxy-α-methylbenzyl Alcohol
  • SMILES OC1=CC=C(C(O)C)C=C1

Description

4-(1-Hydroxyethyl)phenol features a phenolic hydroxyl group conjugated with a pendant hydroxyethyl side chain, enabling dual functionality in synthesis. This structure supports hydrogen bonding and facilitates derivatization at both the aromatic ring and aliphatic alcohol site. The molecule exhibits bench-stable behavior under standard conditions and integrates readily into complex molecular architectures requiring polar, reactive handles.

Application

4-(1-Hydroxyethyl)phenol serves as a versatile phenolic building block for the synthesis of functionalized aromatic compounds. Its hydroxyl and secondary alcohol functionalities enable straightforward derivatization via esterification, etherification, or oxidation to ketone. The molecule exhibits good bench stability and facilitates efficient purification by crystallization or column chromatography. It functions effectively in standard coupling reactions and serves as a key intermediate in the construction of bioactive heterocycles and pharmaceutical scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.4455
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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