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CS-W001157 4
Total: USD 88.00

1H-Indazole-4-carbaldehyde

  • CAS No. 669050-70-8

  • Cat. No. CS-W020008
  • Purity≥97%
  • MDL No.MFCD06738279

*For research and further manufacturing use only, not for direct human use.

1H-Indazole-4-carbaldehyde|CS-W020008

Structure of 669050-70-8

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General Information

  • CAS No. 669050-70-8
  • Cat. No. CS-W020008
  • Purity ≥97%
  • MDL No. MFCD06738279
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O
  • Molecular Weight 146.15
  • Synonym(s) 4-Formylindazole
  • SMILES O=CC1=CC=CC2=C1C=NN2

Description

1H-Indazole-4-carbaldehyde delivers a reactive aldehyde handle at the 4-position of the indazole core, enabling direct coupling in amide bond formation or reductive amination. This electron-deficient heteroaromatic scaffold enhances solubility and stability under standard conditions, facilitating integration into bioactive molecule synthesis.

Application

1H-Indazole-4-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through nucleophilic addition and condensation reactions. Its aldehyde functionality exhibits excellent stability under standard bench conditions and demonstrates broad compatibility with diverse functional groups, facilitating straightforward purification and downstream derivatization. The indazole core provides a rigid, planar platform well-suited for targeted molecular design in kinase inhibitor and CNS-targeted compound development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   1.3754
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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