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CS-W001157 4
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1-Ethyl-1H-pyrazole-4-carbaldehyde

  • CAS No. 304903-10-4

  • Cat. No. CS-0020149
  • Purity≥96%
  • MDL No.MFCD02090888

*For research and further manufacturing use only, not for direct human use.

1-Ethyl-1H-pyrazole-4-carbaldehyde|CS-0020149

Structure of 304903-10-4

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General Information

  • CAS No. 304903-10-4
  • Cat. No. CS-0020149
  • Purity ≥96%
  • MDL No. MFCD02090888
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) 1-Ethylpyrazole-4-carboxaldehyde; 1H-pyrazole-4-carboxaldehyde, 1-ethyl-
  • SMILES O=CC1=CN(CC)N=C1

Description

1-Ethyl-1H-pyrazole-4-carbaldehyde features a pyrazole core functionalized with an ethyl group at N1 and a formyl moiety at C4, enabling direct integration into heterocyclic synthesis. The aldehyde group facilitates nucleophilic addition and condensation reactions, while the electron-deficient pyrazole ring supports regioselective transformations under mild conditions. This bench-stable reagent serves as a key scaffold for medicinal chemistry and materials science applications.

Application

1-Ethyl-1H-pyrazole-4-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazole-based heterocyclic scaffolds. Its aldehyde functionality facilitates reductive amination, condensation reactions, and coupling protocols under standard conditions. The ethyl substituent enhances solubility and metabolic stability, while the pyrazole core provides robust structural integrity. Bench-stable and amenable to purification via flash chromatography, it functions effectively in multi-step synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.89
  • LogP   0.7155
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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