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Structure of 661463-17-8
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4-Bromo-6-fluoroquinoline is a heterocyclic building block featuring orthogonal halogen substituents that enable selective cross-coupling reactions. The electron-deficient quinoline core supports efficient metal-catalyzed transformations, while the fluorine and bromine atoms provide complementary reactivity profiles for sequential functionalization. This compound offers enhanced stability under standard conditions and serves as a key intermediate in pharmaceutical and materials synthesis.
4-Bromo-6-fluoroquinoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogenation pattern. The bromine and fluorine substituents offer orthogonal reactivity for sequential functionalization, while the quinoline core provides inherent stability and favorable pharmacophore characteristics. This compound facilitates efficient synthesis of complex heterocyclic scaffolds and is well-suited for scale-up in API development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P305+P351+P338-P330-P501
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Lot numbers can be found on the outside label of a product: