Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Bromo-6-fluoro-2-methylpyridine

  • CAS No. 375368-83-5

  • Cat. No. CS-W003022
  • Purity≥98%
  • MDL No.MFCD03095092

*For research and further manufacturing use only, not for direct human use.

3-Bromo-6-fluoro-2-methylpyridine|CS-W003022

Structure of 375368-83-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 375368-83-5
  • Cat. No. CS-W003022
  • Purity ≥98%
  • MDL No. MFCD03095092
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrFN
  • Molecular Weight 190.01
  • Synonym(s) 5-bromo-2-fluoro-6-picoline; 3-Bromo-6-fluoro-2-methylpyridine
  • SMILES CC1=C(Br)C=CC(F)=N1

Description

3-Bromo-6-fluoro-2-methylpyridine features a sterically accessible pyridine core with complementary halogen and methyl substituents, enabling selective cross-coupling and functionalization in medicinal chemistry. The electron-deficient ring facilitates palladium-catalyzed reactions under standard conditions.

Application

3-Bromo-6-fluoro-2-methylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The fluorine and methyl groups provide orthogonal functional handles for further derivatization, while the pyridine core offers stability and favorable electronic properties. Its bench-stable nature and ease of purification support efficient synthesis workflows in API development.

Synthesis

  • Route1

    References

    • Liu, Luping; Stelmach, John E.; Natarajan, Swaminathan R.; Chen, Meng-Hsin; Singh, Suresh B.; Schwartz, Cheryl D.; Fitzgerald, Catherine E.; O'Keefe, Stephen J.; Zaller, Dennis M.; Schmatz, Dennis M.; Doherty, James B. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 3979 - 3982

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.29162
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Bromo-6-fluoro-2-methylpyridine sigma3-Bromo-6-fluoro-2-methylpyridine manufacturer3-Bromo-6-fluoro-2-methylpyridine price3-Bromo-6-fluoro-2-methylpyridine structure3-Bromo-6-fluoro-2-methylpyridine SDSbuy 3-Bromo-6-fluoro-2-methylpyridine3-Bromo-6-fluoro-2-methylpyridine supplier3-Bromo-6-fluoro-2-methylpyridine uses3-Bromo-6-fluoro-2-methylpyridine molecular weightprice of 3-Bromo-6-fluoro-2-methylpyridine3-Bromo-6-fluoro-2-methylpyridine chemical name formula of 3-Bromo-6-fluoro-2-methylpyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label