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CS-W001157 4
Total: USD 88.00

3-Bromo-5-fluoro-2-methylpyridine

  • CAS No. 1211542-29-8

  • Cat. No. CS-0056557
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5-fluoro-2-methylpyridine|CS-0056557

Structure of 1211542-29-8

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General Information

  • CAS No. 1211542-29-8
  • Cat. No. CS-0056557
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrFN
  • Molecular Weight 190.01
  • Synonym(s) 3-BroMo-5-fluoro-2-Methyl-pyridine
  • SMILES CC1=NC=C(F)C=C1Br

Description

3-Bromo-5-fluoro-2-methylpyridine features a trifunctional pyridine core with bromo, fluoro, and methyl substituents positioned for orthogonal reactivity. This electron-deficient heterocycle enables seamless cross-coupling and nucleophilic substitution under standard conditions. The molecule exhibits enhanced stability and solubility in polar aprotic solvents, facilitating integration into complex synthetic sequences.

Application

3-Bromo-5-fluoro-2-methylpyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The methyl group provides a site for oxidation or functionalization, while the fluorine and bromine substituents offer tunable electronic effects and synthetic handle diversity. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient access to substituted heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.29162
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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