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Structure of 1162674-74-9
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5-Bromo-3-fluoro-2-methylpyridine is a halogenated pyridine derivative featuring complementary electrophilic and nucleophilic handles. The bromo group enables palladium-catalyzed coupling reactions, while the fluorine atom enhances metabolic stability and modulates electronic properties. The methyl substituent at the 2-position provides steric control and influences regioselectivity in subsequent transformations. This scaffold serves as a key building block in medicinal chemistry and agrochemical synthesis.
5-Bromo-3-fluoro-2-methylpyridine serves as a versatile building block in medicinal chemistry, enabling late-stage functionalization via palladium-catalyzed cross-coupling reactions. The ortho-methyl group enhances regioselectivity in electrophilic substitution, while the bromo and fluoro substituents provide complementary handles for diversification. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient synthesis of complex heterocyclic scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: