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Structure of 654663-32-8
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3-Methoxyisonicotinic acid is a bench-stable, moisture-tolerant pyridine carboxylic acid featuring a methoxy group at the meta position relative to the carboxylate. This electronic and steric configuration enhances solubility in polar organic solvents and facilitates direct incorporation into pharmaceutical scaffolds, coupling reagents, and bioactive molecule synthesis under standard conditions.
3-Methoxyisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-based scaffolds through standard amidation, esterification, and coupling reactions. Its methoxy group enhances solubility and modulates electronic properties, while the carboxylic acid functionality facilitates straightforward derivatization. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it a practical choice for API intermediate development and heterocyclic library construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: