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CS-W001157 4
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Pyrazine-2,3-diamine

  • CAS No. 13134-31-1

  • Cat. No. CS-W003425
  • Purity≥98%
  • MDL No.MFCD07778385

*For research and further manufacturing use only, not for direct human use.

Pyrazine-2,3-diamine|CS-W003425

Structure of 13134-31-1

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General Information

  • CAS No. 13134-31-1
  • Cat. No. CS-W003425
  • Purity ≥98%
  • MDL No. MFCD07778385
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₄
  • Molecular Weight 110.12
  • Synonym(s) 2,3-PYRAZINEDIAMINE
  • SMILES Nc1nccnc1N

Description

Pyrazine-2,3-diamine delivers a highly reactive diamine scaffold featuring two nitrogen atoms at adjacent positions within a heteroaromatic ring. This configuration enables direct incorporation into conjugated systems, facilitating efficient coordination in metal complexes and serving as a key building block for functionalized polyazaheterocycles under mild conditions.

Application

Pyrazine-2,3-diamine serves as a versatile heterocyclic building block for medicinal chemistry and materials science, enabling efficient access to functionalized pyrazine scaffolds. Its two adjacent amine groups facilitate straightforward derivatization via amidation, alkylation, or cross-coupling reactions, offering high functional group tolerance and ease of purification. The compound exhibits good bench stability and is compatible with standard synthetic workflows, making it well-suited for the construction of complex molecular architectures in API development and catalyst design.

Synthesis

  • Route1
    • null|null
      156331-25-8
    • ~85%
    • In-stock
      Pyrazine-2,3-diamine|CS-W003425
      13134-31-1

    References

    • Synthesis, , # 9 p. 931 - 934
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 69, p. 1034,1035 Journal of the American Chemical Society, , vol. 78, p. 242
  • Route3

    References

    • Australian Journal of Chemistry, , vol. 35, # 11 p. 2299 - 2306

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   77.82
  • LogP   -0.359
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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