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CS-W001157 4
Total: USD 88.00

Isonicotinonitrile

  • CAS No. 100-48-1

  • Cat. No. CS-0015782
  • Purity≥98%
  • MDL No.MFCD00006417

*For research and further manufacturing use only, not for direct human use.

Isonicotinonitrile|CS-0015782

Structure of 100-48-1

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General Information

  • CAS No. 100-48-1
  • Cat. No. CS-0015782
  • Purity ≥98%
  • MDL No. MFCD00006417
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄N₂
  • Molecular Weight 104.11
  • Synonym(s) Pyridine-4-carbonitrile
  • SMILES N#CC1=CC=NC=C1

Description

Bromoacetamido-PEG5-azide is a heterobifunctional crosslinking reagent. The bromide (Br) is a very good leaving group for nucleophilic substitution. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG spacer increases solubility in aqueous media.

Synthesis

  • Route1

    References

    • Avalos, Martin; Babiano, Reyes; Cintas, Pedro; Duran, Carlos J.; Higes, Francisco J.; Jimenez, Jose L.; Lopez, Ignacio; Palacios, Juan C. Tetrahedron, 1997 , vol. 53, # 42 p. 14463 - 14480
  • Route2
    • null|null
      462-08-8
    • null|null
      86942-05-4
    • ~%
    • In-stock
      Isonicotinonitrile|CS-0015782
      100-48-1
    • null|null
      86942-12-3

    References

    • Journal of the American Chemical Society, , vol. 105, # 20 p. 6259 - 6263
  • Route3
    • null|null
      108-89-4
    • ~8%
    • In-stock
      γ-Formylpyridine|CS-D1135
      872-85-5
    • In-stock
      Isonicotinonitrile|CS-0015782
      100-48-1
    • Isonicotinamide Isoniazid  Impurity|CS-0229453
      1453-82-3

    References

    • Angewandte Chemie - International Edition, , vol. 51, # 29 p. 7250 - 7253

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332
Precautionary Statements : P261-P264-P280-P302+P352-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   36.68
  • LogP   0.95328
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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