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CS-W001157 4
Total: USD 88.00

3-Methoxypicolinic acid

  • CAS No. 16478-52-7

  • Cat. No. CS-W004949
  • Purity≥97%
  • MDL No.MFCD07367569

*For research and further manufacturing use only, not for direct human use.

3-Methoxypicolinic acid|CS-W004949

Structure of 16478-52-7

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General Information

  • CAS No. 16478-52-7
  • Cat. No. CS-W004949
  • Purity ≥97%
  • MDL No. MFCD07367569
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₃
  • Molecular Weight None
  • Synonym(s) 3-Methoxypyridine-2-carboxylic acid
  • SMILES O=C(C1=NC=CC=C1OC)O

Description

3-Methoxypicolinic acid offers a strategically positioned methoxy group on the picolinic ring, enhancing solubility and modulating electronic properties. This derivative integrates readily into synthetic scaffolds requiring polar, electron-donating functionalities. Its bench-stable nature supports reliable handling in multistep transformations.

Application

3-Methoxypicolinic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds through established functional group transformations. Its ortho-carboxylic acid and methoxy groups offer complementary reactivity for amide coupling, esterification, and cyclization reactions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.7884
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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