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Structure of 651358-83-7
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2-Bromo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine features a boronate ester group flanked by tetramethyl-substituted dioxaborolane rings, enhancing stability and enabling efficient Suzuki-Miyaura coupling. The pyridine core bears a bromide at the 2-position for selective cross-coupling, while the para-directed boronate facilitates regiocontrolled functionalization in synthetic sequences. This compound integrates seamlessly into complex molecule assembly under standard conditions.
2-Bromo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile Suzuki-Miyaura coupling partner, enabling efficient C–C bond formation at the pyridine 2-position. The boronate ester group exhibits high stability under ambient conditions and tolerates a broad range of functional groups, facilitating reliable cross-coupling with aryl and heteroaryl halides. Its bench-stable nature and predictable reactivity make it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: