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CS-W001157 4
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4,4,5,5-Tetramethyl-2-(4-nitrophenyl)-1,3,2-dioxaborolane

  • CAS No. 171364-83-3

  • Cat. No. CS-M0976
  • Purity≥97%
  • MDL No.MFCD02179437

*For research and further manufacturing use only, not for direct human use.

4,4,5,5-Tetramethyl-2-(4-nitrophenyl)-1,3,2-dioxaborolane|CS-M0976

Structure of 171364-83-3

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General Information

  • CAS No. 171364-83-3
  • Cat. No. CS-M0976
  • Purity ≥97%
  • MDL No. MFCD02179437
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆BNO₄
  • Molecular Weight 249.07
  • Synonym(s) 4-Nitrophenylboronic Acid Pinacol Ester
  • SMILES CC(O1)(C)C(C)(C)OB1C2=CC=C([N+]([O-])=O)C=C2

Description

Reactant involved in: Synthesis of aryl azides Arylation of allylic chloridesSyntehsis of RNA conjugatesAlkoxycarbonylationSynthesis of mTOR and PI3K inhibitors as antitumor agentsElectrooxidative synthesis of biaryls

Synthesis

  • Route1
    • null|null
      586-78-7
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • ~88%
    • In-stock
      4,4,5,5-Tetramethyl-2-(4-nitrophenyl)-1,3,2-dioxaborolane|CS-M0976
      171364-83-3

    References

    • Wang, Lianhui; Li, Jingya; Cui, Xiuling; Wu, Yusheng; Zhu, Zhiwu; Wu, Yangjie Advanced Synthesis and Catalysis, 2010 , vol. 352, # 11-12 p. 2002 - 2010
  • Route2

    References

    • Ma, Yudao; Song, Chun; Jiang, Wei; Xue, Guoping; Cannon, John F.; Wang, Xiaomei; Andrus, Merritt B. Organic Letters, 2003 , vol. 5, # 24 p. 4635 - 4638
  • Route3

    References

    • UNIVERSITE DE BORDEAUX 1; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; PUCHEAULT, Mathieu Jonathan Damien; MARCIASINI, Ludovic Daniel Alain; VAULTIER, Michel Patent: WO2014/9169 A1, 2014 ; Location in patent: Page/Page column 56-57 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   61.6
  • LogP   1.894
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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