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CS-W001157 4
Total: USD 88.00

2-(Methylamino)ethanol hydrochloride

  • CAS No. 62640-03-3

  • Cat. No. CS-0542090
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(Methylamino)ethanol hydrochloride|CS-0542090

Structure of 62640-03-3

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General Information

  • CAS No. 62640-03-3
  • Cat. No. CS-0542090
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₁₀ClNO
  • Molecular Weight 111.57
  • Synonym(s) Ethanol, 2-(methylamino)-, hydrochloride
  • SMILES OCCNC.Cl

Description

2-(Methylamino)ethanol hydrochloride is a bench-stable, moisture-tolerant amine derivative featuring a primary amino group and a hydroxyl functionality. This bifunctional compound integrates readily into synthetic sequences requiring both nucleophilic and hydrogen-bonding capabilities. It serves as a key building block in medicinal chemistry and polymer synthesis due to its solubility and reactivity profile under standard conditions.

Application

2-(Methylamino)ethanol hydrochloride serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient synthesis of aminoethyl-containing scaffolds. Its amine and hydroxyl groups offer orthogonal reactivity for conjugation, derivatization, and protection strategies. The hydrochloride salt enhances bench stability and solubility, facilitating handling and purification in standard synthetic workflows.

Synthesis

  • Route1

    References

    • CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin Patent: WO2013/97773 A1, 2013 ; Location in patent: Paragraph 0235; 0311 ;
  • Route2
    • null|null
      108-01-0
    • ~88%
    • In-stock
      2-(Methylamino)ethanol hydrochloride|CS-0542090
      62640-03-3

    References

    • Rosenau, Thomas; Hofinger, Andreas; Potthast, Antje; Kosma, Paul Organic Letters, 2004 , vol. 6, # 4 p. 541 - 544

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.3801
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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