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CS-W001157 4
Total: USD 88.00

Z-Glycinol

  • CAS No. 77987-49-6

  • Cat. No. CS-W004853
  • Purity≥95%
  • MDL No.MFCD00191060

*For research and further manufacturing use only, not for direct human use.

Z-Glycinol|CS-W004853

Structure of 77987-49-6

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General Information

  • CAS No. 77987-49-6
  • Cat. No. CS-W004853
  • Purity ≥95%
  • MDL No. MFCD00191060
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₃
  • Molecular Weight 195.22
  • Synonym(s) N-Z-ethanolamine
  • SMILES O=C(OCC=1C=CC=CC1)NCCO

Application

Z-Glycinol serves as a versatile building block in peptide synthesis, offering a protected glycine derivative with enhanced solubility and stability. Its N-terminal Z-protecting group facilitates efficient coupling reactions, while the primary alcohol enables selective functionalization or derivatization. The molecule exhibits excellent compatibility with standard activation protocols and simplifies purification due to its well-defined polarity and crystalline nature.

Synthesis

  • Route1
    • null|null
      141-43-5
    • null|null
      501-53-1
    • ~99%
    • In-stock
      Z-Glycinol|CS-W004853
      77987-49-6

    References

    • SANKYO COMPANY, LIMITED Patent: US2004/14962 A1, 2004 ; Location in patent: Page/Page column 137 ;
  • Route2
    • null|null
      501-53-1
    • ~73%
    • In-stock
      Z-Glycinol|CS-W004853
      77987-49-6

    References

    • Pfizer Inc. Patent: US6657063 B1, 2003 ; Location in patent: Page column 94-95 ;
  • Route3
    • null|null
      141-43-5
    • null|null
      1885-14-9
    • ~72%
    • In-stock
      Z-Glycinol|CS-W004853
      77987-49-6

    References

    • Pfizer Products Inc. Patent: EP994105 A2, 2000 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   0.9051
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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