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Structure of 402718-29-0
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile features a boronate ester group paired with a nitrile-substituted pyridine core. This combination enables efficient Suzuki-Miyaura coupling under standard conditions while maintaining bench stability and compatibility with diverse reaction environments. The tetramethyl substitution enhances hydrolytic resistance and operational robustness in synthetic workflows.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The nitrile group provides enhanced solubility and metabolic stability, while the tetramethylborolane moiety ensures high reactivity and bench stability. Functions effectively in late-stage functionalization of heterocyclic scaffolds, enabling efficient access to substituted pyridine derivatives under mild reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: