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CS-W001157 4
Total: USD 88.00

Oxetan-2-ylmethanol

  • CAS No. 61266-70-4

  • Cat. No. CS-W019194
  • Molecule weight88.11
  • Purity≥97%
  • MDL No.MFCD00142933

*For research and further manufacturing use only, not for direct human use.

Oxetan-2-ylmethanol|CS-W019194

Structure of 61266-70-4

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General Information

  • CAS No. 61266-70-4
  • Cat. No. CS-W019194
  • Purity ≥97%
  • MDL No. MFCD00142933
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈O₂
  • Molecular Weight 88.11
  • Synonym(s) 2-Oxetanemethanol
  • SMILES OCC1CCO1

Description

Oxetan-2-ylmethanol delivers a strained, three-membered cyclic ether moiety that integrates readily into molecular architectures. This bench-stable compound features a primary hydroxyl group flanked by an oxetane ring, enabling efficient coupling reactions and enhancing solubility in polar media. Its unique combination of ring strain and functional handle supports rapid bioconjugation and drug discovery applications.

Application

Oxetan-2-ylmethanol serves as a versatile building block in medicinal chemistry, enabling the introduction of a strained three-membered oxetane ring with a pendant hydroxyl group. Its bench-stable nature and compatibility with standard functional group manipulations facilitate efficient incorporation into complex molecular architectures. The molecule participates reliably in coupling reactions, acts as a bioisostere for carbonyl or tetrahydrofuran motifs, and supports the synthesis of heterocyclic scaffolds relevant to drug discovery.

Synthesis

  • Route1

    References

    • Tetrahedron Letters, , vol. 21, p. 3051 - 3054
  • Route2
    • null|null
      115845-47-1
    • ~74%
    • In-stock
      Oxetan-2-ylmethanol|CS-W019194
      61266-70-4

    References

    • Fitton, Alan O.; Hill, John; Jane, David E.; Millar, Ross Synthesis, 1987 , # 12 p. 1140 - 1142

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   -0.2324
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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