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CS-W001157 4
Total: USD 88.00

(S)-Oxetan-2-ylmethanol

  • CAS No. 2090778-00-8

  • Cat. No. CS-0099311
  • Purity≥95%
  • MDL No.MFCD31728682

*For research and further manufacturing use only, not for direct human use.

(S)-Oxetan-2-ylmethanol|CS-0099311

Structure of 2090778-00-8

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General Information

  • CAS No. 2090778-00-8
  • Cat. No. CS-0099311
  • Purity ≥95%
  • MDL No. MFCD31728682
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈O₂
  • Molecular Weight 88.11
  • Synonym(s) 2-Oxetanemethanol, (2S)-
  • SMILES OC[C@H]1OCC1

Description

(S)-Oxetan-2-ylmethanol is a chiral oxetane derivative featuring a hydroxymethyl group at the 2-position, offering enhanced metabolic stability and improved solubility in medicinal chemistry applications. This bench-stable scaffold integrates readily into bioactive molecules, where its strained ring system enhances binding affinity through favorable dipole interactions.

Application

(S)-Oxetan-2-ylmethanol serves as a valuable building block in medicinal chemistry, enabling the introduction of a strained oxetane ring with defined stereochemistry. Its hydroxymethyl functionality facilitates derivatization and acts as a versatile handle for coupling reactions, while the oxetane moiety enhances metabolic stability and solubility in drug candidates. The compound exhibits good bench stability and compatibility with standard synthetic protocols, making it well-suited for use in API development and combinatorial library synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H302-H315-H319-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   -0.2324
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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