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CS-W001157 4
Total: USD 88.00

(S)-Oxetane-2-carboxylic acid

  • CAS No. 2241107-29-7

  • Cat. No. CS-0148269
  • Purity≥97%
  • MDL No.MFCD31690962

*For research and further manufacturing use only, not for direct human use.

(S)-Oxetane-2-carboxylic acid|CS-0148269

Structure of 2241107-29-7

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General Information

  • CAS No. 2241107-29-7
  • Cat. No. CS-0148269
  • Purity ≥97%
  • MDL No. MFCD31690962
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆O₃
  • Molecular Weight 102.09
  • Synonym(s) (2S)-oxetane-2-carboxylic acid
  • SMILES O=C([C@H]1OCC1)O

Description

(S)-Oxetane-2-carboxylic acid is a chiral, bench-stable building block featuring a strained four-membered oxetane ring fused to a carboxylic acid group. This configuration enables direct incorporation into bioactive molecules, where the oxetane moiety enhances solubility and metabolic stability. The stereochemistry at the 2-position supports predictable reactivity in asymmetric synthesis, facilitating efficient access to complex pharmaceutical intermediates under standard conditions.

Application

(S)-Oxetane-2-carboxylic acid serves as a key chiral building block in medicinal chemistry, enabling the construction of oxetane-containing heterocycles prevalent in bioactive molecules. Its well-defined stereochemistry and bench-stable nature facilitate reliable incorporation into drug candidates. The carboxylic acid group supports direct derivatization or coupling reactions, while the strained oxetane ring enhances metabolic stability and binding affinity. This compound functions as a versatile scaffold for targeted synthesis of pharmaceutical intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   -0.1401
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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