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CS-W001157 4
Total: USD 88.00

3-Hydroxytetrahydrofuran

  • CAS No. 453-20-3

  • Cat. No. CS-M0786
  • Purity≥98%
  • MDL No.MFCD00005374

*For research and further manufacturing use only, not for direct human use.

3-Hydroxytetrahydrofuran|CS-M0786

Structure of 453-20-3

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General Information

  • CAS No. 453-20-3
  • Cat. No. CS-M0786
  • Purity ≥98%
  • MDL No. MFCD00005374
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈O₂
  • Molecular Weight None
  • Synonym(s) Tetrahydrofuran-3-ol
  • SMILES OC1COCC1

Description

3-Hydroxytetrahydrofuran serves as a key oxygenated heterocyclic scaffold in synthetic intermediates, offering a rigid, polar ring system that enhances solubility and metabolic stability. This bench-stable compound integrates readily into complex molecular architectures via selective functionalization at the hydroxyl group, enabling efficient access to bioactive derivatives.

Synthesis

  • Route1
    • null|null
      3068-00-6
    • ~98%
    • In-stock
      3-Hydroxytetrahydrofuran|CS-M0786
      453-20-3

    References

    • MITSUI CHEMICALS, INC. Patent: WO2005/121111 A1, 2005 ; Location in patent: Page/Page column 33 ;
  • Route2
    • null|null
      627-27-0
    • ~81%
    • In-stock
      3-Hydroxytetrahydrofuran|CS-M0786
      453-20-3

    References

    • Bhaumik, Asim; Tatsumi, Takashi Chemical Communications, 1998 , # 4 p. 463 - 464
  • Route3
    • null|null
      38115-87-6
    • ~%
    • In-stock
      3-Hydroxytetrahydrofuran|CS-M0786
      453-20-3
    • null|null
      121-43-7
    • null|null
      3068-00-6

    References

    • ALLIANT TECHSYSTEMS INC. Patent: US2011/118511 A1, 2011 ; Location in patent: Page/Page column 3-4 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P264-P280-P305+P351+P338-P337+P313

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   -0.2324
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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