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CS-W001157 4
Total: USD 88.00

2,5-Dibromobenzoic acid

  • CAS No. 610-71-9

  • Cat. No. CS-W002104
  • Purity≥95%
  • MDL No.MFCD00016494

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromobenzoic acid|CS-W002104

Structure of 610-71-9

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General Information

  • CAS No. 610-71-9
  • Cat. No. CS-W002104
  • Purity ≥95%
  • MDL No. MFCD00016494
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄Br₂O₂
  • Molecular Weight None
  • Synonym(s) Benzoic acid, 2,5-dibromo-
  • SMILES BrC1=CC(C(O)=O)=C(Br)C=C1

Description

2,5-Dibromobenzoic acid features two bromine atoms positioned at the 2 and 5 ring locations, delivering enhanced electrophilicity and stability for cross-coupling reactions. This electron-deficient aromatic carboxylic acid integrates readily into complex scaffolds, offering a robust handle for further functionalization in synthetic organic chemistry and materials science applications.

Application

2,5-Dibromobenzoic acid serves as a versatile building block for the synthesis of brominated aromatic scaffolds, enabling palladium-catalyzed cross-coupling reactions with high functional group tolerance. Its stability under standard reaction conditions and ease of purification make it well-suited for applications in medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      124-38-9
    • In-stock
      1,4-Dibromobenzene|CS-0000003
      106-37-6
    • ~86%
    • In-stock
      2,5-Dibromobenzoic acid|CS-W002104
      610-71-9

    References

    • Lulinski, Sergiusz; Serwatowski, Janusz; Szczerbinska, Magdalena European Journal of Organic Chemistry, 2008 , # 10 p. 1797 - 1801
  • Route2

    References

    • Journal of the Chemical Society, , vol. 61, p. 1029 Chemische Berichte, , vol. 13, p. 963 Chemische Berichte, , vol. 14, p. 417
  • Route3

    References

    • Tetrahedron Letters, , vol. 49, # 3 p. 415 - 418

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.9098
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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