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CS-W001157 4
Total: USD 88.00

2-Bromo-5-fluorobenzoic acid

  • CAS No. 394-28-5

  • Cat. No. CS-W014777
  • Purity≥98%
  • MDL No.MFCD00142874

*For research and further manufacturing use only, not for direct human use.

2-Bromo-5-fluorobenzoic acid|CS-W014777

Structure of 394-28-5

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General Information

  • CAS No. 394-28-5
  • Cat. No. CS-W014777
  • Purity ≥98%
  • MDL No. MFCD00142874
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrFO₂
  • Molecular Weight 219.01
  • Synonym(s) BUTTPARK 19\01-66
  • SMILES O=C(O)C1=CC(F)=CC=C1Br

Description

A purine nucleoside anti-metabolite. Toxic to nondividing lymphocytes and monocytes

Application

2-Bromo-5-fluorobenzoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling direct functionalization at the ortho-bromo and meta-fluoro positions. Its stability under standard reaction conditions facilitates palladium-catalyzed cross-couplings and nucleophilic aromatic substitution. The carboxylic acid group allows for straightforward derivatization into amides, esters, or acyl chlorides, supporting efficient route optimization in medicinal chemistry campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2864
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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