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CS-W001157 4
Total: USD 88.00

2-Bromo-4-fluorobenzoic acid

  • CAS No. 1006-41-3

  • Cat. No. CS-W002266
  • Purity≥98%
  • MDL No.MFCD00055370

*For research and further manufacturing use only, not for direct human use.

2-Bromo-4-fluorobenzoic acid|CS-W002266

Structure of 1006-41-3

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General Information

  • CAS No. 1006-41-3
  • Cat. No. CS-W002266
  • Purity ≥98%
  • MDL No. MFCD00055370
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrFO₂
  • Molecular Weight 219.01
  • Synonym(s) 4-Fluoro-2-bromobenzoic acid
  • SMILES Fc1ccc(c(c1)Br)C(=O)O

Description

N-(alfa-Maleimidoacetoxy)succinimide is a small molecule featuring both an NHS ester and a maleimide. The NHS is easily displaced by amine nucleophiles to form amides with target molecules while maleimide is a thiol-specific covalent moiety which is used to label reduced cysteines in proteins.

Synthesis

  • Route1

    References

    • Mei, Tian-Sheng; Giri, Ramesh; Maugel, Nathan; Yu, Jin-Quan Angewandte Chemie - International Edition, 2008 , vol. 47, # 28 p. 5215 - 5219
  • Route2

    References

    • Collection of Czechoslovak Chemical Communications, , vol. 40, # 3 p. 719 - 737
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 28, p. 1759 - 1762

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2864
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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