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CS-W001157 4
Total: USD 88.00

O-Isobutylhydroxylamine Hydrochloride

  • CAS No. 6084-58-8

  • Cat. No. CS-0136014
  • Purity≥97%
  • MDL No.MFCD00060208

*For research and further manufacturing use only, not for direct human use.

O-Isobutylhydroxylamine Hydrochloride|CS-0136014

Structure of 6084-58-8

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General Information

  • CAS No. 6084-58-8
  • Cat. No. CS-0136014
  • Purity ≥97%
  • MDL No. MFCD00060208
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₂ClNO
  • Molecular Weight 125.60
  • Synonym(s) Isobutyloxyamine Hydrochloride
  • SMILES NOCC(C)C.Cl

Description

O-Isobutylhydroxylamine Hydrochloride offers a sterically hindered hydroxylamine functionality ideal for selective N-oxidation and oxime formation under mild conditions. This bench-stable reagent features enhanced solubility in polar solvents and resists premature decomposition, enabling reliable performance in synthetic workflows requiring controlled nitrogen-based transformations.

Application

O-Isobutylhydroxylamine Hydrochloride serves as a reliable reagent for the synthesis of oximes and related nitrogen-containing heterocycles. Its bench-stable form facilitates straightforward handling and purification, while the isobutyl group provides favorable steric and electronic properties for selective transformations. It functions effectively in standard condensation reactions with carbonyl compounds under mild conditions, enabling efficient access to functionalized intermediates in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      52026-51-4
    • ~32%
    • In-stock
      O-Isobutylhydroxylamine Hydrochloride|CS-0136014
      6084-58-8

    References

    • High; Prior; Bell; Rangachari Journal of Pharmacology and Experimental Therapeutics, 1999 , vol. 288, # 2 p. 490 - 501
  • Route2
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      5618-62-2
    • ~%
    • In-stock
      O-Isobutylhydroxylamine Hydrochloride|CS-0136014
      6084-58-8

    References

    • Journal of Agricultural and Food Chemistry, , vol. 55, # 26 p. 10857 - 10863

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   0.9545
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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