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CS-W001157 4
Total: USD 88.00

O-Butylhydroxylamine hydrochloride

  • CAS No. 4490-82-8

  • Cat. No. CS-0106180
  • Purity≥97%
  • MDL No.MFCD00487631

*For research and further manufacturing use only, not for direct human use.

O-Butylhydroxylamine hydrochloride|CS-0106180

Structure of 4490-82-8

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General Information

  • CAS No. 4490-82-8
  • Cat. No. CS-0106180
  • Purity ≥97%
  • MDL No. MFCD00487631
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₂ClNO
  • Molecular Weight 125.60
  • Synonym(s) O-butylhydroxylamine HCl
  • SMILES NOCCCC.[H]Cl

Description

O-Butylhydroxylamine hydrochloride offers a stable, moisture-tolerant source of hydroxylamine functionality for nucleophilic transformations. This bench-stable reagent integrates readily into synthetic sequences requiring controlled nitrogen insertion, enabling efficient access to oximes and related heterocycles under standard conditions.

Application

O-Butylhydroxylamine hydrochloride serves as a stable, bench-ready reagent for the synthesis of oximes and related nitrogen-containing heterocycles. Its functional group tolerance enables reliable coupling with aldehydes and ketones under mild conditions, facilitating efficient purification and scalable access to key intermediates in medicinal chemistry and agrochemical development.

Synthesis

  • Route1
    • null|null
      60302-19-4
    • ~99%
    • In-stock
      O-Butylhydroxylamine hydrochloride|CS-0106180
      4490-82-8

    References

    • Khomutov, Maxim A.; Mandal, Swati; Weisell, Janne; Saxena, Neiha; Simonian, Alina R.; Vepsalainen, Jouko; Madhubala, Rentala; Kochetkov, Sergey N. Amino Acids, 2010 , vol. 38, # 2 p. 509 - 517
  • Route2
    • null|null
      23362-50-7
    • ~68%
    • In-stock
      O-Butylhydroxylamine hydrochloride|CS-0106180
      4490-82-8

    References

    • Andrews, Luke E.; Bonin, Antonio M.; Fransson, Linda E.; Gillson, Ashley-Mae E.; Glover, Stephen A. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2006 , vol. 605, # 1-2 p. 51 - 62
  • Route3
    • null|null
      5622-77-5
    • ~%
    • In-stock
      O-Butylhydroxylamine hydrochloride|CS-0106180
      4490-82-8

    References

    • Huang, Jia-Xing; Jia, Yue-Mei; Liang, Xiao-Mei; Zhu, Wei-Juan; Zhang, Jian-Jun; Dong, Yan-Hong; Yuan, Hui-Zu; Qi, Shu-Hua; Wu, Jin-Ping; Chen, Fu-Heng; Wang, Dao-Quan Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 26 p. 10857 - 10863

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.0986
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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