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CS-W001157 4
Total: USD 88.00

Oxindole

  • CAS No. 59-48-3

  • Cat. No. CS-M2997
  • Purity≥98%
  • MDL No.MFCD00005711

*For research and further manufacturing use only, not for direct human use.

Oxindole|CS-M2997

Structure of 59-48-3

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General Information

  • CAS No. 59-48-3
  • Cat. No. CS-M2997
  • Purity ≥98%
  • MDL No. MFCD00005711
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO
  • Molecular Weight 133.15
  • Synonym(s) 2-Indolinone
  • SMILES O=C1NC2=C(C=CC=C2)C1

Description

Phosphatidylglycerol (PG) is one of the important lipid, found in the membranes of bacteria. But in mammals, PG accounts for only 12 mol% of phospholipids. This lipid is abundantly present in the lung surfactant. thus pointing to an important role therein.10:0 PG (1,2-didecanoyl-sn-glycero-3-phospho-(1-rac-glycerol)) may be used as a component in the liposomes, labeled with -pyrene-C10-PG. It may also be used in the preparation of small unilamellar vesicle (SUV) liposomes.

Application

Oxindole serves as a foundational scaffold in medicinal chemistry, enabling the construction of diverse heterocyclic systems through well-established functionalization at the 3-position. Its inherent stability and compatibility with common coupling reactions facilitate efficient synthesis of biologically relevant compounds. The molecule functions as a key building block for API development, particularly in kinase inhibitors and CNS-targeted therapeutics, offering predictable reactivity and straightforward purification.

Synthesis

  • Route1

    References

    • Deng; Konopelski Organic letters, 2001 , vol. 3, # 19 p. 3001 - 3004
  • Route2
    • Indole, ≥99%|CS-1268948
      120-72-9
    • ~35%
    • In-stock
      Oxindole|CS-M2997
      59-48-3
    • null|null
      17646-95-6

    References

    • Applied Catalysis A: General, , vol. 470, p. 427 - 433
  • Route3

    References

    • Applied Catalysis A: General, , vol. 470, p. 427 - 433

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.1812
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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