Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Methylindolin-2-one

  • CAS No. 3484-35-3

  • Cat. No. CS-0005465
  • Purity≥95%
  • MDL No.MFCD02379906

*For research and further manufacturing use only, not for direct human use.

5-Methylindolin-2-one|CS-0005465

Structure of 3484-35-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 3484-35-3
  • Cat. No. CS-0005465
  • Purity ≥95%
  • MDL No. MFCD02379906
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO
  • Molecular Weight 147.17
  • Synonym(s) 5-methyl-1,3-dihydro-2H-indol-2-one
  • SMILES O=C1NC2=C(C=C(C)C=C2)C1

Description

5-Methylindolin-2-one is a bench-stable, electron-rich heterocycle featuring a fused indoline core with a methyl substituent at the 5-position. This structural motif delivers enhanced solubility and stability in polar solvents, enabling efficient integration into synthetic routes for bioactive molecules. The carbonyl group facilitates nucleophilic addition and cyclization reactions under mild conditions.

Application

5-Methylindolin-2-one serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization at the C3 and C5 positions. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient derivatization. The ketone functionality supports nucleophilic addition and reduction, while the indolinone core provides structural rigidity and hydrogen-bonding potential relevant to target binding.

Synthesis

  • Route1

    References

    • Tetrahedron Letters, , vol. 55, # 14 p. 2238 - 2242
  • Route2
    • null|null
      106-49-0
    • null|null
      79-04-9
    • ~85%
    • In-stock
      5-Methylindolin-2-one|CS-0005465
      3484-35-3

    References

    • Ultrasonics Sonochemistry, , vol. 18, # 5 p. 1143 - 1147
  • Route3
    • null|null
      106-49-0
    • ~%
    • In-stock
      5-Methylindolin-2-one|CS-0005465
      3484-35-3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 24 p. 7349 - 7353

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.48962
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Methylindolin-2-one sigma5-Methylindolin-2-one manufacturer5-Methylindolin-2-one price5-Methylindolin-2-one structure5-Methylindolin-2-one SDSbuy 5-Methylindolin-2-one5-Methylindolin-2-one supplier5-Methylindolin-2-one uses5-Methylindolin-2-one molecular weightprice of 5-Methylindolin-2-one5-Methylindolin-2-one chemical name formula of 5-Methylindolin-2-one
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label