Lot numbers can be found on the outside label of a product:
tert-Butyl 2-oxoindoline-1-carboxylate
-
CAS No. 214610-10-3
- Cat. No. CS-0038092
- Purity≥97%
- MDL No.MFCD09032873
*For research and further manufacturing use only, not for direct human use.
Structure of 214610-10-3
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 214610-10-3
- Cat. No. CS-0038092
- Purity ≥97%
- MDL No. MFCD09032873
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₃H₁₅NO₃
- Molecular Weight 233.26
- Synonym(s) tert-butyl 2-oxo-2,3-dihydroindole-1-carboxylate
- SMILES O=C(N1C(CC2=C1C=CC=C2)=O)OC(C)(C)C
Description
tert-Butyl 2-oxoindoline-1-carboxylate features a bench-stable carbamate protecting group that enables reliable access to functionalized indoline scaffolds. The electron-deficient oxo group facilitates nucleophilic addition and cyclization reactions under mild conditions, while the tert-butyl moiety ensures compatibility with standard deprotection protocols. This compound serves as a key intermediate in the synthesis of biologically active indoline derivatives.
Application
tert-Butyl 2-oxoindoline-1-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to indoline scaffolds via reductive amination or catalytic hydrogenation. The tert-butyl carbamate group provides excellent stability and facilitates straightforward deprotection under mild acidic conditions. Its compatibility with diverse functional groups and utility in constructing biologically relevant heterocycles make it a practical choice for medicinal chemistry and process development workflows.
Synthesis
-
References
-
Akai, Shuji; Tsujino, Toshiaki; Naka, Tadaatsu; Tanimoto, Kouichi; Kita, Yasuyuki Tetrahedron Letters, 2001 , vol. 42, # 41 p. 7315 - 7317
-
-
Route2
-
In-stock
59-48-3 -
1538-75-6 - ~78%
-
In-stock
214610-10-3
References
-
Arizpe, Alicia; Sayago, Francisco J.; Jimenez, Ana I.; Ordonez, Mario; Cativiela, Carlos European Journal of Organic Chemistry, 2011 , # 16 p. 3074 - 3081
-
-
Route3
-
1026846-93-4
- ~%
-
In-stock
214610-10-3
References
-
Padwa, Albert; Wang, Qiu Journal of Organic Chemistry, 2006 , vol. 71, # 8 p. 3210 - 3220
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H317
|
|
|
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 46.61
- LogP 2.5108
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- tert-Butyl 2-oxoindoline-1-carboxylate sigmatert-Butyl 2-oxoindoline-1-carboxylate manufacturertert-Butyl 2-oxoindoline-1-carboxylate pricetert-Butyl 2-oxoindoline-1-carboxylate structuretert-Butyl 2-oxoindoline-1-carboxylate SDSbuy tert-Butyl 2-oxoindoline-1-carboxylatetert-Butyl 2-oxoindoline-1-carboxylate suppliertert-Butyl 2-oxoindoline-1-carboxylate usestert-Butyl 2-oxoindoline-1-carboxylate molecular weightprice of tert-Butyl 2-oxoindoline-1-carboxylatetert-Butyl 2-oxoindoline-1-carboxylate chemical name formula of tert-Butyl 2-oxoindoline-1-carboxylate