Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Methylpiperidin-4-ol hydrochloride

  • CAS No. 586375-35-1

  • Cat. No. CS-B1024
  • Purity≥95%
  • MDL No.MFCD11044137

*For research and further manufacturing use only, not for direct human use.

4-Methylpiperidin-4-ol hydrochloride|CS-B1024

Structure of 586375-35-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 586375-35-1
  • Cat. No. CS-B1024
  • Purity ≥95%
  • MDL No. MFCD11044137
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClNO
  • Molecular Weight 151.63
  • Synonym(s) 4-Hydroxy-4-methylpiperidine hydrochloride; 4-Methylpiperidin-4-ol hydrochloride; 4-Methylpiperidin-4-ol Hydrochloride Salt
  • SMILES CC1(CCNCC1)O.Cl

Description

4-Methylpiperidin-4-ol hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a tertiary alcohol functionality. This compound integrates readily into medicinal chemistry scaffolds due to its polar yet lipophilic character. The protonated piperidine nitrogen enhances solubility in aqueous systems while maintaining favorable membrane permeability. It serves as a key building block for targeted synthesis of bioactive molecules.

Application

4-Methylpiperidin-4-ol hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to saturated nitrogen heterocycles. Its bench-stable hydrochloride salt form enhances handling and solubility, while the primary alcohol functionality supports straightforward derivatization via esterification, etherification, or coupling reactions. The molecule functions effectively in late-stage functionalization and scaffold diversification due to its favorable reactivity profile and compatibility with common synthetic transformations.

Synthesis

  • Route1

    References

    • H. LUNDBECK A/S Patent: US2011/92475 A1, 2011 ; Location in patent: Page/Page column 19 ;
  • Route2
    • 1-Benzyl-4-methylpiperidin-4-ol|CS-0279387
      3970-66-9
    • ~89%
    • In-stock
      4-Methylpiperidin-4-ol hydrochloride|CS-B1024
      586375-35-1

    References

    • EXELIXIS, INC.; RICE, Kenneth Patent: WO2012/71509 A2, 2012 ; Location in patent: Page/Page column 154 ; WO 2012/071509 A2
  • Route3
    • Benzyl 4-hydroxy-4-methylpiperidine-1-carboxylate|CS-0049826
      169750-57-6
    • ~95%
    • In-stock
      4-Methylpiperidin-4-ol hydrochloride|CS-B1024
      586375-35-1

    References

    • Takeda Pharmaceutical Company Limited Patent: EP2392573 A1, 2011 ; Location in patent: Page/Page column 41 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   32.26
  • LogP   0.5426
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Methylpiperidin-4-ol hydrochloride sigma4-Methylpiperidin-4-ol hydrochloride manufacturer4-Methylpiperidin-4-ol hydrochloride price4-Methylpiperidin-4-ol hydrochloride structure4-Methylpiperidin-4-ol hydrochloride SDSbuy 4-Methylpiperidin-4-ol hydrochloride4-Methylpiperidin-4-ol hydrochloride supplier4-Methylpiperidin-4-ol hydrochloride uses4-Methylpiperidin-4-ol hydrochloride molecular weightprice of 4-Methylpiperidin-4-ol hydrochloride4-Methylpiperidin-4-ol hydrochloride chemical name formula of 4-Methylpiperidin-4-ol hydrochloride
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label