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Structure of 57963-11-8
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4,5-Dimethylpyridin-2-amine features a pyridine core with methyl groups at the 4 and 5 positions, enhancing electron density at the nitrogen lone pair. This substitution pattern improves basicity and nucleophilicity compared to unsubstituted pyridine derivatives. The compound serves as a robust ligand in transition metal catalysis and integrates readily into functionalized heterocycles. Its bench-stable nature supports reliable use in synthetic workflows.
4,5-Dimethylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted pyridine scaffolds via standard coupling and functionalization reactions. Its electron-rich heterocyclic core exhibits favorable stability and compatibility with common synthetic protocols, facilitating efficient derivatization for target-oriented synthesis. The molecule functions effectively as a ligand in transition metal catalysis and supports ortho-directed metallation due to its nitrogen positioning.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: