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CS-W001157 4
Total: USD 88.00

3-Bromo-2-chloroaniline

  • CAS No. 56131-46-5

  • Cat. No. CS-0042828
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Bromo-2-chloroaniline|CS-0042828

Structure of 56131-46-5

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General Information

  • CAS No. 56131-46-5
  • Cat. No. CS-0042828
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrClN
  • Molecular Weight 206.47
  • Synonym(s) None
  • SMILES NC1=CC=CC(Br)=C1Cl

Description

3-Bromo-2-chloroaniline features a bromine substituent at the meta position and a chlorine atom at the ortho position relative to the amino group, creating a highly functionalized aryl scaffold. This electron-deficient aniline derivative enables selective coupling reactions in pharmaceutical synthesis and serves as a key intermediate for bioactive heterocycles under standard conditions.

Application

3-Bromo-2-chloroaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation into heterocyclic scaffolds via electrophilic substitution or palladium-catalyzed coupling. Its complementary halogenation pattern offers orthogonal reactivity for sequential functionalization, while its bench-stable nature facilitates handling and purification in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.6847
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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