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CS-W001157 4
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Propargyl-PEG1-acid

  • CAS No. 55683-37-9

  • Cat. No. CS-0108409
  • Purity≥97%
  • MDL No.MFCD10689189

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG1-acid|CS-0108409

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General Information

  • CAS No. 55683-37-9
  • Cat. No. CS-0108409
  • Purity ≥97%
  • MDL No. MFCD10689189
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈O₃
  • Molecular Weight 128.13
  • Synonym(s) None
  • SMILES O=C(O)CCOCC#C

Description

Makes extremely durable layers. Sharp separations for amino acids, sugars and other hydrophilic substances. Development time as short as 2hours for 8 plates.

Application

Propargyl-PEG1-acid serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, combining a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (CuAAC) with a carboxylic acid for amide coupling. Its short PEG spacer enhances solubility and reduces steric hindrance, enabling efficient conjugation in aqueous media. The compound exhibits excellent bench stability, simplifies purification via standard protocols, and functions reliably in the synthesis of functionalized biomolecules, probes, and responsive materials.

Synthesis

  • Route1

    References

    • Tsutsui, Hideyuki; Matsuura, Maya; Makino, Kazuishi; Nakamura, Seiichi; Nakajima, Makoto; Kitagaki, Shinji; Hashimoto, Shunichi Israel Journal of Chemistry, 2001 , vol. 41, # 4 p. 283 - 295

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.1109
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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