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CS-W001157 4
Total: USD 88.00

Propargyl-PEG2-acid

  • CAS No. 1859379-85-3

  • Cat. No. CS-0068466
  • Purity≥98%
  • MDL No.MFCD29764323

*For research and further manufacturing use only, not for direct human use.

Propargyl-PEG2-acid|CS-0068466

Structure of 1859379-85-3

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General Information

  • CAS No. 1859379-85-3
  • Cat. No. CS-0068466
  • Purity ≥98%
  • MDL No. MFCD29764323
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂O₄
  • Molecular Weight 172.18
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCC#C

Description

-Estradiol-6-one 6-(O-carboxymethyloxime) is a derivative of 17-estradiol.

Application

Propargyl-PEG2-acid serves as a versatile bifunctional linker for conjugation and polymer chemistry, combining the reactivity of a terminal alkyne with a stable, hydrophilic PEG spacer and a carboxylic acid handle. It facilitates efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) and enables amide coupling under standard conditions. The molecule exhibits excellent solubility in aqueous and organic media, bench stability, and ease of purification—ideal for bioconjugation, drug delivery systems, and functionalized surface modifications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   0.1275
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   7

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