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CS-W001157 4
Total: USD 88.00

(4-Fluorophenyl)(phenyl)methanamine

  • CAS No. 55095-26-6

  • Cat. No. CS-0197278
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-Fluorophenyl)(phenyl)methanamine|CS-0197278

Structure of 55095-26-6

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General Information

  • CAS No. 55095-26-6
  • Cat. No. CS-0197278
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂FN
  • Molecular Weight 201.24
  • Synonym(s) OTAVA-BB 1179198
  • SMILES NC(C1=CC=CC=C1)C2=CC=C(F)C=C2

Description

This bench-stable arylamine features a fluorinated phenyl ring paired with a parent phenyl group, delivering enhanced electron-withdrawing character and improved metabolic stability. The tertiary amine center enables efficient coupling in transition metal-catalyzed reactions and facilitates incorporation into bioactive scaffolds for medicinal chemistry applications.

Application

(4-Fluorophenyl)(phenyl)methanamine serves as a versatile arylamine building block in medicinal chemistry, enabling the construction of biologically relevant scaffolds. Its fluorinated aryl moiety enhances metabolic stability and modulates electronic properties, while the benzylic amine functionality supports facile derivatization via acylation, alkylation, or reductive amination. The compound exhibits good bench stability and is compatible with standard purification protocols, facilitating integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.8738
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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