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CS-W001157 4
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1-[(2s)-2-(hydroxymethyl)pyrrolidin-1-yl]ethan-1-one

  • CAS No. 66158-68-7

  • Cat. No. CS-0256427
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-[(2s)-2-(hydroxymethyl)pyrrolidin-1-yl]ethan-1-one|CS-0256427

Structure of 66158-68-7

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General Information

  • CAS No. 66158-68-7
  • Cat. No. CS-0256427
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight 143.18
  • Synonym(s) 1-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-ethanone
  • SMILES CC(=O)N1CCC[C@H]1CO

Synthesis

  • Route1
    • null|null
      108-24-7
    • In-stock
      (2S)-2-Pyrrolidinemethanol|CS-D1460
      23356-96-9
    • ~96%
    • In-stock
      1-[(2s)-2-(hydroxymethyl)pyrrolidin-1-yl]ethan-1-one|CS-0256427
      66158-68-7

    References

    • Takahashi, Hiroshi; Kawabata, Akihiro; Higashiyama, Kimio Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 4 p. 1604 - 1607
  • Route2
    • L-Proline Enalapril  Impurity|CS-0229432
      147-85-3
    • ~%
    • In-stock
      1-[(2s)-2-(hydroxymethyl)pyrrolidin-1-yl]ethan-1-one|CS-0256427
      66158-68-7

    References

    • Schurig, V.; Hintzer, K.; Leyrer, U.; Mark, C.; Pitchen, P.; Kagan, H. B. Journal of Organometallic Chemistry, 1989 , vol. 370, p. 81 - 96
  • Route3
    • null|null
      75-36-5
    • In-stock
      (2S)-2-Pyrrolidinemethanol|CS-D1460
      23356-96-9
    • ~%
    • In-stock
      1-[(2s)-2-(hydroxymethyl)pyrrolidin-1-yl]ethan-1-one|CS-0256427
      66158-68-7

    References

    • Xu, Qianyong; Wang, Hui; Pan, Xinfu; Chan, Albert S.C; Yang, Teng-Kuei Tetrahedron Letters, 2001 , vol. 42, # 35 p. 6171 - 6173

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   -0.0104
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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