Lot numbers can be found on the outside label of a product:
Diethyl 2-formylsuccinate
-
CAS No. 5472-38-8
- Cat. No. CS-0140696
- Purity≥95%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 5472-38-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 5472-38-8
- Cat. No. CS-0140696
- Purity ≥95%
- MDL No. None
- Storage -20°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₁₄O₅
- Molecular Weight 202.20
- Synonym(s) diethyl formylsuccinate
- SMILES O=C(OCC)C(C=O)CC(OCC)=O
Description
Diethyl 2-formylsuccinate is a bifunctional diester bearing an aldehyde group at the C2 position, enabling direct incorporation into conjugation and cyclization workflows. This reactive scaffold facilitates efficient access to heterocyclic frameworks and functionalized intermediates under mild conditions.
Application
Diethyl 2-formylsuccinate serves as a versatile diester building block featuring an aldehyde group flanked by two ester functionalities, enabling sequential functionalization in synthetic sequences. It facilitates aldol condensations, Michael additions, and heterocycle formation under standard conditions. The molecule exhibits good bench stability and is readily purified by distillation or column chromatography, making it well-suited for use in multi-step syntheses of complex organic scaffolds and pharmaceutical intermediates.
Synthesis
-
Route1
-
109-94-4 -
In-stock
123-25-1 - ~97%
-
In-stock
5472-38-8
References
-
European Molecular Biology Laboratory; F. Hoffmann-La Roche AG; WOLKERSTORFER, Andrea; SZOLAR, Oliver; HANDLER, Norbert; CUSACK, Stephen; SAUVAITRE, Thibault; SIMON, Céline; MORICE, Christophe; GIETHLEN, Bruno; LANGER, Thierry; SMITH, Mark; SO, Sung-Sau; CLASSEN-HOUBEN, Dirk; BUSCHMANN, Helmut Patent: US2013/317022 A1, 2013 ; Location in patent: Paragraph 0536-0538 ;
-
-
Route2
-
585-68-2
-
64-17-5
- ~%
-
In-stock
5472-38-8
References
-
Wislicenus; Boeklen; Reuthe Justus Liebigs Annalen der Chemie, 1908 , vol. 363, p. 358
-
-
Route3
-
60-29-7
-
In-stock
623-91-6 - ~%
-
In-stock
5472-38-8
References
-
Adkins; Krsek Journal of the American Chemical Society, 1948 , vol. 70, p. 385 Journal of the American Chemical Society, 1949 , vol. 71, p. 3053,3054
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 69.67
- LogP 0.3178
- H_Acceptors 5
- H_Donors 0
- Rotatable_Bonds 6
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Diethyl 2-formylsuccinate sigmaDiethyl 2-formylsuccinate manufacturerDiethyl 2-formylsuccinate priceDiethyl 2-formylsuccinate structureDiethyl 2-formylsuccinate SDSbuy Diethyl 2-formylsuccinateDiethyl 2-formylsuccinate supplierDiethyl 2-formylsuccinate usesDiethyl 2-formylsuccinate molecular weightprice of Diethyl 2-formylsuccinateDiethyl 2-formylsuccinate chemical name formula of Diethyl 2-formylsuccinate