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CS-W001157 4
Total: USD 88.00

Di-tert-Butyl fumarate

  • CAS No. 7633-38-7

  • Cat. No. CS-0139693
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Di-tert-Butyl fumarate|CS-0139693

Structure of 7633-38-7

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General Information

  • CAS No. 7633-38-7
  • Cat. No. CS-0139693
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀O₄
  • Molecular Weight 228.28
  • Synonym(s) Di-tert-butyl maleate
  • SMILES O=C(OC(C)(C)C)/C=C/C(OC(C)(C)C)=O

Description

Di-tert-butyl fumarate features a sterically hindered fumarate core that resists hydrolysis under standard conditions. This bench-stable diester integrates readily into polymerization workflows, enabling controlled incorporation of bulky substituents in synthetic macromolecules.

Application

Di-tert-butyl fumarate serves as a stable, bench-ready diester building block for conjugated diene synthesis and Michael addition reactions. Its sterically shielded tert-butyl groups enhance stability and facilitate purification, while the trans-configuration ensures predictable stereochemical outcomes in cycloaddition and condensation processes. Functions effectively in standard enolate chemistry and heterocycle construction workflows.

Synthesis

  • Route1
    • null|null
      1663-39-4
    • ~95%
    • In-stock
      Di-tert-Butyl fumarate|CS-0139693
      7633-38-7

    References

    • Choi; Choon Woo Lee; Chatterjee; Grubbs Journal of the American Chemical Society, 2001 , vol. 123, # 42 p. 10417 - 10418
  • Route2
    • In-stock
      Dimethyl fumarate|CS-0909
      624-49-7
    • null|null
      75-65-0
    • ~34%
    • In-stock
      Di-tert-Butyl fumarate|CS-0139693
      7633-38-7

    References

    • Chung, Yu-Chiang; Janmanchi, Damodar; Wu, Hsyueh-Liang Organic Letters, 2012 , vol. 14, # 11 p. 2766 - 2769
  • Route3
    • null|null
      627-63-4
    • null|null
      75-65-0
    • ~94%
    • In-stock
      Di-tert-Butyl fumarate|CS-0139693
      7633-38-7

    References

    • Arora, Paramjit S.; Van, Que N.; Famulok, Michael; Shaka; Nowick, James S. Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 9 p. 1421 - 1428

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   2.226
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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