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CS-W001157 4
Total: USD 88.00

4-Hydroxybenzohydrazide

  • CAS No. 5351-23-5

  • Cat. No. CS-W013295
  • Purity≥96%
  • MDL No.MFCD00007605

*For research and further manufacturing use only, not for direct human use.

4-Hydroxybenzohydrazide|CS-W013295

Structure of 5351-23-5

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General Information

  • CAS No. 5351-23-5
  • Cat. No. CS-W013295
  • Purity ≥96%
  • MDL No. MFCD00007605
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₂
  • Molecular Weight 152.15
  • Synonym(s) p-Hydroxybenzoylhydrazine
  • SMILES O=C(NN)C1=CC=C(O)C=C1

Description

-Ionone, an end ring analog of -carotene, is a volatile carotenoid that contributes to the fragrance in many flowers, including petunia (Petunia hybrida).-Ionone may be used as a reference standard in the determination of -ionone in wine using solid-phase extraction followed by gas chromatography with mass spectrometry (GC-MS).

Application

4-Hydroxybenzohydrazide serves as a versatile building block in the synthesis of heterocyclic scaffolds and bioactive molecules. Its phenolic hydroxyl and hydrazide functional groups enable reliable condensation reactions, facilitating the construction of pyrazole, triazole, and oxadiazole derivatives. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in iterative synthetic sequences for medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Zaheer, Muhammad; Zia-Ur-Rehman, Muhammad; Rahman, Salma; Ahmed, Naveed; Chaudhary, Muhammad Nawaz Journal of the Chilean Chemical Society, 2012 , vol. 57, # 4 p. 1492 - 1496
  • Route2
    • 4-Hydroxybenzoic acid  Cetirizine Impurity|CS-0167040
      99-96-7
    • ~84%
    • In-stock
      4-Hydroxybenzohydrazide|CS-W013295
      5351-23-5

    References

    • Raghav, Neera; Singh, Mamta European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 231 - 242
  • Route3
    • Ethyl 4-hydroxybenzoate Erlotinib Impurity|CS-0167068
      120-47-8
    • ~%
    • In-stock
      4-Hydroxybenzohydrazide|CS-W013295
      5351-23-5

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2> 52, p. 234

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.35
  • LogP   -0.0043
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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