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CS-W001157 4
Total: USD 88.00

PEG3-O-CH2COOH

  • CAS No. 51951-05-4

  • Cat. No. CS-0100058
  • Purity≥95%
  • MDL No.MFCD24479936

*For research and further manufacturing use only, not for direct human use.

PEG3-O-CH2COOH|CS-0100058

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General Information

  • CAS No. 51951-05-4
  • Cat. No. CS-0100058
  • Purity ≥95%
  • MDL No. MFCD24479936
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆O₆
  • Molecular Weight 208.21
  • Synonym(s) PROTAC Linker 8
  • SMILES OCCOCCOCCOCC(O)=O

Description

PEG3-O-CH2COOH features a short polyethylene glycol chain terminated by a reactive carboxylic acid group, enabling efficient conjugation in bioconjugation workflows. This water-soluble linker combines stability with ease of coupling, facilitating site-specific modifications in peptide and protein engineering applications.

Application

PEG3-O-CH2COOH serves as a versatile bifunctional linker for conjugation workflows, combining the solubility and biocompatibility of triethylene glycol with a terminal carboxylic acid. It enables efficient amide coupling reactions under standard conditions, facilitating site-specific attachment to amines in peptides, proteins, and biomolecules. The PEG3 spacer provides enhanced flexibility and reduced steric hindrance, while the stable, bench-ready structure supports straightforward purification and reproducible functionalization in synthetic and bioconjugation applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   85.22
  • LogP   -0.8869
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   10

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